Software Package Details
Software Name: Gorgon
Software Licensing: other (open source)
Software URL: http://gorgon.wustl.edu
Software Reference: http://www.ncbi.nlm.nih.gov/pubmed/20885381, http://www.ncbi.nlm.nih.gov/pubmed/20888467
- interactive modeling in subnanometer resolution density maps
Gorgon is an interactive molecular modeling system specifically geared towards near-atomic and intermediate resolution density maps of macromolecular complexes. The long term goal of the gorgon project is to be able to address to every part of the molecular modeling pipeline starting from the initial volumetric reconstruction.
Gorgon currently provides the following feature categories:
* Visualization: A comprehensive visualization framework for volumetric data (iso-contours, cross-sections and solid rendering), geometric skeletons, secondary structure elements and atomic models (PDB). * Geometric operations: Many geometric operations such as skeletonization (binary / grayscale and interactive), smoothing, resampling, cropping, etc. are provided. * Secondary structure identification: SSEHunter is now integrated into Gorgon, which lets you to find the locations of Alpha Helices and Beta Sheets given a low-resolution density map of a molecule. * Protein structure analysis: We provide tools which allow users to find the correspondence between predicted secondary structure elements in the sequence and the observed secondary structure elements in the volume. * Protein backbone tracing: The c-alpha backbone of a protein can be easily traced manually or semi-automatically using the many supporting elements offered by Gorgon.
Gorgon is being developed as a collaboration between Washington University in St. Louis and Baylor College of Medicine.