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root @ 2010/07/12
Created by root @ 2010/07/09 23:38:58
Last revised by root @ 2010/07/12 09:17:56
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Folder Name: Rotavirus
Folder Description:
From Wikipedia: Rotavirus is the most common cause of severe diarrhoea among infants and young children, and is one of several viruses that cause infections often called stomach flu, despite having no relation to influenza. It is a genus of double-stranded RNA virus in the family Reoviridae. By the age of five, nearly every child in the world has been infected with rotavirus at least once. However, with each infection, immunity develops, subsequent infections are less severe, and adults are rarely affected. There are five species of this virus, referred to as A, B, C, D, and E. Rotavirus A, the most common, causes more than 90% of infections in humans.
Rotavirus has been studied by more than one group over the years, but for the challenge, we focus strictly on the results from Grigorieff's group where the VP6 component was extracted from multiple positions in the icosahedral unit and averaged to produce a high-resolution (3.8 A) density map for that component.